Whooping cough is a respiratory disease caused by a bacterial infection. Dedicated to pushing the boundaries of whooping cough diagnostics, our company is at the forefront of developing custom IVD solutions. By creating groundbreaking DNA, antibody, and microbial reagents/kits as well as automated diagnostic devices, we strive to solve whooping cough diagnostic challenges and revolutionize the detection and management of this disease.
Overview of Whooping Cough
Whooping cough, medically known as pertussis, is a highly contagious bacterial infection that primarily affects the respiratory tract, especially the nose and throat. The disease is characterized by severe coughing and difficulty breathing. Whooping cough is caused by Bordetella pertussis and can lead to serious complications, especially for infants and young children. Whooping cough remains a major public health problem worldwide, and the development of effective diagnostic tools is important for the accurate identification and prevention and control of the disease.
Fig. 1 Effects of pertussis toxin on immune response. (Scanlon, K., et al., 2019)
Diagnostic Biomarkers for Whooping Cough
Identifying specific biomarkers associated with Bordetella pertussis infection can aid in early diagnosis, distinguishing it from other respiratory conditions with similar symptoms. Biomarker-based tests offer rapid and precise detection, allowing for timely interventions and appropriate therapeutic strategies.
Bacterial DNA
Bordetella pertussis DNA can be used as a direct indicator of the presence of bacteria in a sample, aiding in the diagnosis of whooping cough. Detection of bacterial DNA by molecular techniques such as PCR allows for rapid and sensitive identification of Bordetella pertussis.
Antibodies
Serological tests for anti-pertussis toxin (PT) and anti-filamentous hemagglutinin (FHA) antibodies are helpful in diagnosing whooping cough. Measuring antibody levels in the serum helps differentiate between recent infection and past exposure to Bordetella pertussis.
IVD Kits for Whooping Cough
In vitro diagnostic (IVD) kits tailored for whooping cough diagnosis play a crucial role in guaranteeing precise, swift, and standardized detection of Bordetella pertussis infection. Presently, multiple IVD kits are accessible in the market, serving as vital tools for the efficient management of pertussis.
| Kits |
Applications |
Detection Methods |
| Bordetella Pertussis DNA Detection Kit |
Qualitative detection of Bordetella pertussis bacteria specific DNA. |
Real-time PCR |
| Antibody Detection Kit |
Detection of antibodies against Bordetella pertussis such as IgA, IgG and IgM in serum or plasma samples. |
ELISA |
Our Services
At our company, we specialize in developing tailored IVD solutions for whooping cough. Our unwavering commitment is to create cutting-edge DNA, antibody, and microbial detection kits to facilitate rapid diagnosis and timely intervention for Bordetella pertussis infection. Through innovative accompanying diagnostic equipment, our goal is to advance the efficient and automated diagnosis of whooping cough.
Furthermore, our offerings encompass point-of-care testing (POCT) and companion diagnostic development tailored for whooping cough, aiding in expediting diagnosis and individualized therapeutics for whooping cough. If you are interested in our services, please don't hesitate to reach out to us for further information and pricing details on the services we offer.
Reference
- Scanlon, K., C. Skerry, and N. Carbonetti. "Association of pertussis toxin with severe pertussis disease. Toxins (Basel) 11 (7)." (2019).
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
