Norovirus infection is a highly contagious disease. Our company is committed to advancing the diagnosis of this disease through cutting-edge technologies and tailored solutions. By developing innovative IVD reagents/kits and compact diagnostic devices, we aim to address the diagnostic challenges of norovirus infection and facilitate rapid diagnosis and early intervention.
Introduction to Norovirus Infection
Norovirus is a highly contagious virus that causes gastroenteritis, with symptoms including nausea, vomiting, and diarrhea. Norovirus is notorious for its rapid transmission through close contact, contaminated food, or surfaces. It is a leading cause of foodborne illnesses, with approximately 685 million cases reported globally each year, notably affecting over 200 million children. Given its prevalence, advanced diagnostic tools are necessary for accurate and timely detection.
Fig. 1 Schematic diagram of the norovirus replication cycle. (Hassan, E., and M. T. Baldridge., 2019)
IVD Development for Norovirus Infection
The development of advanced diagnostic tools for detecting norovirus is crucial in preventing the spread of this highly contagious pathogen. Customized in vitro diagnostic (IVD) kits tailored for norovirus can rapidly and accurately detect the virus, enabling healthcare providers to promptly intervene and prevent further spread of the virus.
Viral RNA Detection Kit
The viral RNA genome of norovirus is a key biomarker for its detection. RT-PCR and loop-mediated isothermal amplification (LAMP) can specifically and quantitatively detect viral RNA, thus enabling early diagnosis and infection monitoring.
Antigen Detection Kit
Detection of viral antigens, such as the norovirus capsid protein, is a common approach for diagnosing norovirus infections. ELISAs targeting specific viral antigens can provide rapid and sensitive detection of the virus in clinical samples.
POCT Kit
Point-of-care testing (POCT) for norovirus infection allows for rapid on-site testing in a variety of settings, including clinics, emergency rooms and remote areas. POCT kits can provide an immediate diagnosis, allowing for timely infection control measures.
IVD Kits for Norovirus Infection
In vitro diagnostic (IVD) kits designed for the diagnosis of norovirus infection are indispensable in public health initiatives aimed at containing the dissemination of this extremely contagious pathogen. Presently, multiple IVD kits are available in the market for the detection of norovirus infection.
| Kits |
Applications |
Detection Methods |
| Norovirus RT-PCR Kit |
Qualitative detection and differentiation of norovirus genogroup I (GI) and II (GII) specific RNA in stool samples. |
RT-PCR |
| Norovirus Antigen Test Kit |
Direct qualitative detection of norovirus GI and GII antigens. |
Latex Chromatography Assay |
| Norovirus Rapid Test Kit |
Qualitatively determining the presence of norovirus in human fecal samples. |
Lateral Flow Assay |
Our Services
By delving into the pathogenesis and metabolic pathways of norovirus infection, we are committed to developing innovative IVD solutions to accurately identify and effectively manage this infectious disease. Our services include the development of viral RNA and antigen detection kits as well as supporting diagnostic devices. Our goal is to revolutionize the diagnosis of norovirus infection by creating cutting-edge IVD products.
Developing point-of-care testing (POCT) using norovirus biomarkers has the potential to revolutionize the diagnosis and management of infections. Our companion diagnostic development service focuses on integrating diagnostic tests with specific therapies to achieve personalized therapeutics for norovirus infections.
If you are interested in our services, please don't hesitate to reach out to us for further information and pricing details on the services we offer.
Reference
- Hassan, E., and M. T. Baldridge. "Norovirus encounters in the gut: multifaceted interactions and disease outcomes. Mucosal Immunol 12: 1259–1267." (2019).
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
