Advancing diagnostic solutions for candidiasis is a crucial component of disease care. Leveraging a skilled team of researchers and scientists specializing in candidiasis, our company is dedicated to the creation of cutting-edge in vitro diagnostic (IVD) tools. Moreover, we provide point-of-care testing (POCT) and companion diagnostic development services to accelerate the diagnosis process and customize therapeutics effectively for candidiasis.
Overview of Cytomegalovirus Infection
Cytomegalovirus (CMV) infection, caused by a member of the herpesvirus family, has emerged as a significant global health concern due to its prevalence and potential complications. CMV can be transmitted through different bodily fluids including saliva, urine, blood, etc. While CMV affects individuals of all age groups, it poses particular risks to pregnant women, newborns, and individuals with compromised immune systems, potentially leading to severe manifestations affecting multiple organ systems.
Fig. 1 Cytomegalovirus infection in developing brain. (Krstanović, Fran, et al., 2021)
Diagnostic Biomarkers for Cytomegalovirus Infection
In the field of cytomegalovirus (CMV) infection diagnostics, the strategic utilization of biomarkers such as antigens, antibodies, and DNA plays a crucial role in accurate and comprehensive disease assessment. Developing user-friendly and convenient diagnostic tools utilizing these biomarkers allows for rapid diagnosis of CMV infection, monitoring of disease progression, and effective therapeutic strategy formulation.
Antigen Biomarkers
pp65 is a phosphoprotein that is abundantly expressed in CMV-infected cells and is a broad target for detecting CMV antigens in samples. Immediate early antigen is one of the first viral proteins expressed during CMV replication and is an important marker for early detection.
Antibody Biomarkers
IgM and IgG antibodies play a vital role in the immune response to CMV infection. Elevated IgG antibody titers or the presence of IgM antibodies may indicate active CMV infection. Detecting antibody levels and patterns assists in distinguishing between primary and recurrent infections.
DNA Biomarkers
CMV DNA is a direct indicator of the presence of the virus in a host biological sample. The polymerase chain reaction (PCR) is an exceptionally sensitive and specific technique for detecting CMV DNA, enabling the quantification of viral load and the monitoring of viral replication.
IVD Kits for Cytomegalovirus Infection
In vitro diagnostic (IVD) kits designed for diagnosing CMV infection are essential tools for effective detection, quantification, monitoring, and management of CMV infections. Timely diagnosis is essential, particularly for at-risk groups like pregnant women, newborns, and individuals with compromised immune systems, as it allows for the prompt implementation of therapeutics and management protocols.
| Kits |
Applications |
Detection Methods |
| Cytomegalovirus (CMV) Nucleic Acid Detection Kit |
Detection and quantification of CMV specific DNA in plasma, whole blood, and urine. |
PCR |
| Cytomegalovirus (CMV) IgM Antibody Detection Kit |
Detection of specific IgM antibodies in samples. |
ELISA |
| Cytomegalovirus (CMV) IgG Antibody Rapid Test Kit |
Point-of-care test (POCT) for cytomegalovirus IgG antibodies. |
Lateral Flow Assay |
| Cytomegalovirus (CMV) Early Antigen Detection Kit |
Qualitative detection and identification of CMV immediate early antigen (IEA) in cell cultures. |
Immunofluorescence |
Our Services
Our company specializes in offering advanced IVD solutions for infectious diseases like cytomegalovirus (CMV) infection. We are dedicated to crafting customized antigen, antibody, and DNA test kits to enhance early identification and efficient management of CMV infection. These kits are utilized alongside supplementary diagnostic devices to optimize detection sensitivity and specificity.
To facilitate rapid diagnosis and personalized therapeutics of cytomegalovirus (CMV) infection, we offer point-of-care testing (POCT) and companion diagnostic development services. These services play a vital role in enhancing the precision and efficiency of CMV infection diagnosis, aiding in the formulation of personalized care strategies for impacted individuals.
If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
Reference
- Krstanović, Fran, et al. "Cytomegalovirus infection and inflammation in developing brain." Viruses 13.6 (2021): 1078.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
