Candidiasis, caused by the fungus Candida, is a fungal infection. Through our innovative work in candidiasis research, we lead the way in creating state-of-the-art IVD tools to improve the efficient management of candidiasis. Serving as your reliable research ally in candidiasis diagnostics, we deliver unmatched assistance to fulfill your research requirements.
Introduction to Candidiasis
Candidiasis, a fungal infection triggered by an excess of yeast, notably Candida albicans, represents a substantial global health concern. This condition arises when the equilibrium between yeast and beneficial bacteria is disturbed, leading to an infection. Candidiasis manifests in various ways, including vaginal candidiasis, cutaneous candidiasis, oral candidiasis (thrush), and invasive candidiasis, all presenting distinct symptoms, which complicates the diagnostic process.
Fig. 1 Schematic representation of the immune response triggered by Candida albicans. (Cheng, Shih-Chin, et al., 2012)
Diagnostic Biomarkers for Candidiasis
Diagnostic biomarkers play a crucial role in the early detection and monitoring of candidiasis. Integrating antigens, antibodies, and DNA biomarkers associated with candidiasis into diagnostic tests enables a comprehensive understanding of the condition, facilitating accurate and timely diagnosis, therapeutic response monitoring, and recurrent infection surveillance.
Antigens
Various cell wall components of Candida, such as mannan, β-D-glucan, and enolase, can serve as antigenic biomarkers. Detecting these antigens in blood or urine aids in diagnosing various forms of candidiasis, including invasive infections.
Antibodies
Testing for anti-Candida antibodies in serum can provide valuable information about the immune response to infection. Elevated antibody levels may indicate active or recent Candida infection and help confirm the diagnosis and monitor disease progression.
DNA
Candida DNA in a sample serves as a direct indicator of the presence of the fungus. By targeting specific regions of Candida DNA, molecular techniques such as PCR can identify the presence of the fungus with high sensitivity and specificity.
IVD Kits for Candidiasis
In vitro diagnostic (IVD) kits tailored for candidiasis offer swift and user-friendly diagnostic solutions. These kits boast high sensitivity and specificity, targeting distinct Candida antigens, antibodies, or DNA markers. This specificity aids in distinguishing among different Candida species, enabling early disease detection and prompt intervention.
| Kits |
Applications |
Detection Methods |
| Candida Albicans Real-time PCR Kit |
The kit detects the RPR1 gene, which has been identified as a good genetic marker for Candida albicans. |
Real-time PCR |
| Candida Antigen Detection Kit |
The kit is a quantitative and qualitative test for the detection of Candida antigens in serum or plasma laboratory samples. |
ELISA |
| Candida Albicans IgG ELISA Kit |
This kit is used to detect anti-Candida albicans IgG antibodies in serum and plasma samples. |
ELISA |
Our Services
By conducting extensive research on the pathogenesis and diagnostic biomarkers of candidiasis, our company is dedicated to innovating IVD solutions for precise identification and efficient management of this infectious condition. Our offerings encompass the creation of antigen, antibody, DNA, microbial test kits, and supplementary diagnostic devices. Our objective is to transform candidiasis diagnosis through the development of state-of-the-art IVD products.
Additionally, we offer point-of-care testing (POCT) and companion diagnostic development services tailored to candidiasis. These services enable the design of portable and user-friendly IVD tools, fostering swift identification and personalized therapeutics of candidiasis.
If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
Reference
- Cheng, Shih-Chin, et al. "Interplay between Candida albicans and the mammalian innate host defense." Infection and immunity 80.4 (2012): 1304-1313.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
