The diverse range of symptoms exhibited in cases of streptococcal infection poses a considerable challenge in the diagnostic process. Dedicated to delivering holistic IVD solutions for the detection of streptococcal infections, our company specializes in crafting antigen, antibody, and DNA test kits along with accompanying diagnostic apparatus. Our objective is to revolutionize the detection and management of this infectious disease by developing advanced diagnostic tools.
Overview of Streptococcal Infections
Streptococcal infections, caused by gram-positive aerobic organisms known as streptococci, encompass a spectrum of disorders affecting various organ systems. These infections, including pharyngitis, pneumonia, skin infections, sepsis, and endocarditis, present a significant healthcare challenge worldwide. Below are some common streptococci.
- Streptococcus Pyogenes
- Streptococcus Agalactiae
- Viridans Streptococci
- Group C and G Streptococci
- Streptococcus Pneumoniae
- Enterococcus Species
- Streptococcus Mutans
- And More
Fig. 1 Mechanism of action of Group A Streptococcus infection. (Brouwer, Stephan, et al., 2023)
Diagnostic Biomarkers for Streptococcal Infections
The intricate nature of streptococcal infections poses a challenge in accurate diagnosis due to their diverse and complex symptoms. Critical in this process are diagnostic biomarkers encompassing specific antigens, antibodies, and DNA, pivotal for the precise identification, tracking, and control of streptococcal infections. The development of diagnostic assays utilizing these biomarkers stands to enhance the precision and effectiveness of diagnostic procedures, significantly refining the diagnostic landscape for streptococcal infections.
Antigens
Antigen testing plays a key role in the rapid diagnosis of streptococcal infections. For example, the presence of group A Streptococcus antigen in a specimen indicates the presence of an active streptococcal infection, most commonly associated with pharyngitis.
Antibodies
Specific antibodies produced by the immune system in response to streptococcal infection are important diagnostic biomarkers. For example, anti-streptolysin O (ASO) and anti-DNase B antibodies are commonly measured in serum to indicate a recent streptococcal infection.
DNA
Streptococcal DNA in samples is a specific biomarker in the early stages of the disease. They help identify the presence of streptococcal pathogens and differentiate between various streptococcal species. PCR methods can detect streptococcal DNA quickly and accurately.
IVD Kits for Streptococcal Infections
In vitro diagnostic (IVD) kits provide a rapid and reliable method to identify the presence of Streptococcus pathogens. By combining a variety of diagnostic biomarkers into one easy-to-use kit, IVD kits simplify the diagnostic process, enhance diagnostic accuracy, and improve therapeutic outcomes by facilitating early detection and targeted management of Streptococcus infections.
| Kits |
Applications |
Detection Methods |
| Group B Streptococcus Real-time PCR Kit |
Rapid identification of Group B Streptococcus (GBS, Streptococcus agalactiae) DNA. |
Real-time PCR |
| Group A Streptococcus Direct Detection Kit |
Rapid test for Group A Streptococcus (Streptococcus Pyogenes) DNA. |
Real-time PCR |
| Anti-Streptolysin O (ASO) Latex Test Kit |
Qualitative and semiquantitative detection of ASO in serum. |
Slide Agglutination Test |
| Anti-DNase B Antibody Detection Kit |
Detection of anti-DNase B antibody levels in samples. |
ELISA |
Our Services
Based on the diagnostic challenges faced by streptococcal infections, our company is committed to investing in advanced technologies and professional talents to promote the development of IVD solutions. By overcoming technical limitations, we are able to design cutting-edge IVD products for the diagnosis of streptococcal infections, including various types of IVD kits and supporting diagnostic equipment.
In addition, our offerings extend to encompass point-of-care testing (POCT) and companion diagnostic development services tailored for addressing streptococcal infections. These specialized services empower you to create portable, user-friendly IVD tools, enabling swift identification and customized therapeutic solutions for streptococcal infections.
If you are interested in our services, please don't hesitate to reach out to us for further information and pricing details on the services we offer.
Reference
- Brouwer, Stephan, et al. "Pathogenesis, epidemiology and control of Group A Streptococcus infection." Nature Reviews Microbiology 21.7 (2023): 431-447.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
