Hepatitis C is a viral infection that affects the liver. Drawing on our innovative work in hepatitis C research, we lead the way in developing state-of-the-art diagnostic tools to improve the efficient management of hepatitis C. Serving as your dependable ally in hepatitis C diagnostic exploration, we offer unmatched support to address your research requirements.
Overview of Hepatitis C
Hepatitis C is an infectious disease triggered by the hepatitis C virus (HCV). The primary mode of HCV transmission is through exposure to infected blood, fostering chronic liver inflammation and enduring harm. Individuals harboring hepatitis C frequently exhibit no symptoms for extended periods, fostering undetected instances and consequently heightening disease transmission rates. This underscores the significance of expansive screening and diagnostic campaigns to promptly identify and manage cases.
Fig. 1 Structure of hepatitis C virus (HCV). (Elgretli W, et al., 2023)
Diagnostic Biomarkers for Hepatitis C
Diagnostic biomarkers are crucial for precise diagnosis, tracking therapeutic responses, evaluating liver health, and forecasting the progression of hepatitis C in infected individuals. Consistent monitoring of these biomarkers empowers healthcare providers to devise effective therapeutic plans and achieve personalized therapy.
Detection of hepatitis C virus (HCV) RNA in blood confirms active infection and helps monitor viral load during therapeutics.
The presence of antibodies against HCV indicates exposure to the virus. Additional testing is required to differentiate between active and past infections.
Increased concentrations of liver enzymes, including alanine aminotransferase (ALT) and aspartate aminotransferase (AST), signal liver inflammation and injury resulting from HCV infection.
IVD Development for Hepatitis C
In the development of in vitro diagnostic (IVD) solutions for hepatitis C, a range of testing kits can be designed to aid in the accurate detection and management of the infection. Some potential IVD kits that can be developed for hepatitis C include:
HCV RNA Detection Kits
These kits usually use PCR technology to detect HCV RNA in blood samples to confirm active infection and monitor viral load during therapeutics.
Liver Enzyme Measurement Kits
These kits typically use chemical assays, such as enzyme kinetics, to measure liver enzyme levels in the blood. The enzyme levels can serve as indicators of the severity of liver inflammation and damage attributed to HCV infection.
HCV Antibody Detection Kits
Employing immunoassays like ELISA, these IVD kits are utilized to detect specific HCV antibodies in the blood, aiding in the diagnosis of past or present infections.
Our Services
At our company, we offer a diverse array of IVD solutions tailored to address intricate diagnostic requirements of hepatitis C. Our proficiency lies in crafting IVD regents and kits that target HCV RNA, antibodies, and disease-associated metabolites, facilitating early detection and precise diagnosis of this significant infectious disease. Leveraging state-of-the-art diagnostic devices, our primary objective is to streamline and automate diagnostic procedures, ultimately enhancing operational efficacy.
IVD Product Development Services
Our specialized point-of-care testing (POCT) development service is committed to creating rapid and user-friendly diagnostic tools tailored for hepatitis C. Additionally, our companion diagnostic development services are geared towards offering personalized therapeutic insights for individuals with hepatitis C by crafting IVD tests and accompanying apparatus.
If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
Reference
- Elgretli W, Chen T, Kronfli N, et al. Hepatitis C virus-lipid interplay: pathogenesis and clinical impact[J]. Biomedicines, 2023, 11(2): 271.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
