Early and accurate diagnosis of Chlamydia is crucial for prompt therapeutics and prevention of complications. Through the creation of advanced IVD reagents/kits and compact diagnostic devices, we strive to tackle the intricacies of Chlamydia pathogenesis and diagnostic obstacles, revolutionizing the detection and therapies of this infectious condition.
Overview of Chlamydia
Caused by the bacterium Chlamydia trachomatis, Chlamydia is a prevalent sexually transmitted infection (STI) recognized for its often asymptomatic presentation. This covert attribute frequently results in undetected and untreated infections, increasing the likelihood of complications like pelvic inflammatory disease (PID), infertility, and ectopic pregnancy. The infection can also affect various body parts beyond the genital region, including the eyes, throat, and anus.
Fig. 1 Pathogenesis of Chlamydia. (Tian Q, et al., 2024)
Diagnostic Biomarkers for Chlamydia
Accurate and efficient diagnostic tools are urgently required for the prevention and management of Chlamydia, which is frequently asymptomatic but can lead to severe complications. Diagnostic biomarkers are crucial in identifying Chlamydia infection and providing insights into its presence and progression.
Bacterial DNA
Identifying Chlamydia trachomatis DNA in a sample is fundamental to confirming the presence of the pathogen. Techniques such as PCR and transcription-mediated amplification (TMA) are employed to amplify and detect unique fragments of bacterial DNA, allowing for precise identification of the bacterium.
Chlamydia Antigens
Chlamydia antigen detection is another important aspect of Chlamydia diagnostics. Major outer membrane protein (MOMP) and Chlamydial lipopolysaccharide (LPS) are crucial targets in antigen detection assays, enabling the swift diagnosis of Chlamydia infections.
IVD Kits for Chlamydia
In vitro diagnostic (IVD) kits offer a dependable, precise, and effective approach to diagnose Chlamydia. Through the utilization of specific biomarkers like bacterial DNA or antigens, these kits enable the swift identification of bacteria within a sample.
| Kits |
Applications |
Detection Methods |
| Chlamydia Trachomatis PCR Kit |
Qualitative detection of Chlamydia trachomatis DNA. |
PCR |
| Chlamydia Antigen Detection Kit |
Identifying the presence of Chlamydia trachomatis by detecting MOMP or LPS. |
Rapid chromatographic immunoassay |
| Chlamydia Rapid Test Kit |
Qualitative detection of Chlamydia trachomatis antigen in samples. (POCT) |
Rapid immunoassay |
Our Services
Our company is committed to advancing
IVD solutions for Chlamydia. Our primary emphasis lies in the development of
DNA and
antigen detection kits specifically designed for Chlamydia trachomatis, alongside
microbial detection kits geared towards the accurate detection of pathogen presence. Through the creation of antigen
point-of-care tests (POCT), our objective is to enable swift pathogen screening at home.
IVD Product Development Services
Through the innovation of state-of-the-art
diagnostic equipment, we have notably enhanced the automation and efficacy of Chlamydia diagnostics. Our focus on
companion diagnostic development services underscores the integration of diagnostic testing with therapeutic measures to craft individualized therapeutic protocols.
If you are interested in our services, please don't hesitate to
reach out to us for further information and pricing details on the services we offer.
Reference
- Tian Q, Zhang T, Shu C, et al. Diverse animal models for Chlamydia infections: unraveling pathogenesis through the genital and gastrointestinal tracts[J]. Frontiers in Microbiology, 2024, 15: 1386343.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
