Ebola virus disease (EVD) is an infectious illness characterized by a remarkably high mortality rate. Leveraging a team of proficient researchers and scientists specializing in EVD, our company is committed to the advancement of sophisticated IVD solutions tailored for EVD. We also offer point-of-care testing (POCT) and companion diagnostic development services to expedite prompt diagnosis and personalized therapeutic options for EVD.
Introduction to Ebola Virus Disease
Ebola virus disease (EVD), caused by the Ebolavirus, is a severe and often fatal illness in humans. The disease is characterized by fever, severe internal bleeding, and organ failure. EVD is predominantly transmitted to humans from wild animals and disseminates through human-to-human transmission. The outbreak of EVD can lead to high mortality rates, highlighting the urgent need for accurate and rapid diagnostic tools for early detection and containment.
Fig. 1 The transmission patterns of Ebola between animals and humans. (Heeney J L., 2015)
IVD Development for Ebola Virus Disease
In the timely and precise identification of pathogens like the Ebola virus, the pivotal role of in vitro diagnostic (IVD) tools comes to the forefront. Swift and reliable diagnostic testing is crucial for prompt disease management, epidemic control, and implementation of effective therapeutic plans.
Viral RNA Detection
The gold standard method for confirming Ebola virus infection is through molecular techniques such as RT-PCR to detect viral RNA. Developing quantitative RT-PCR diagnostic tools to determine the viral load in samples aids in disease monitoring and therapeutic assessment.
Antigen Detection
Developing IVD tools targeting specific Ebola virus antigens, such as nucleoprotein (NP) or viral glycoprotein (GP), or creating rapid diagnostic tests based on lateral flow immunoassays could help to quickly and accurately diagnose Ebola virus infection.
Antibody Detection
The development of IgM and IgG antibody detection kits using enzyme-linked immunosorbent assays (ELISA) or lateral flow technology is important for understanding the immune response after Ebola virus infection and distinguishing acute infection from past infection.
IVD Kits for Ebola Virus Disease
The development and utilization of in vitro diagnostic (IVD) kits play a crucial role in the diagnosis, management, and control of Ebola virus disease (EVD). Currently, several IVD kits targeting EVD have been approved for use.
|
Kits |
Applications |
Detection Methods |
| Ebola Virus Antigen Test Kit |
Qualitative detection of Ebola virus antigens in whole blood, serum or plasma samples. |
Lateral flow assays |
| Ebola Virus RNA Detection Kit |
Detecting the presence of Ebola virus RNA in samples. |
RT-PCR |
| Ebola Virus Antibody Test Kit |
Detection of IgM and IgG antibodies produced by the immune system in response to Ebola virus infection. |
ELISA |
Our Services
Our company is dedicated to advancing IVD solutions for infectious diseases like Ebola virus disease (EVD). Our primary focus is on developing RNA, antigen, and antibody detection kits for Ebola virus to accurately identify EVD infections. By creating rapid EVD detection, our goal is to facilitate quick pathogen screening in resource-constrained settings.
IVD Product Development Services
By developing state-of-the-art complementary diagnostic devices, we optimize the diagnostic process for Ebola virus disease (EVD), improving its automation and effectiveness. Our companion diagnostic development service involves the design and validation of companion diagnostic tests that help guide the selection of appropriate therapies for individuals with EVD.
If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
Reference
- Heeney J L. Hidden reservoirs[J]. Nature, 2015, 527(7579): 453-455.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
