Autoimmune diseases represent a group of complex conditions. Our company is dedicated to advancing autoimmune disease diagnostics through a range of specialized services. Our expertise includes developing IVD reagents and kits for accurate disease detection, and designing and manufacturing IVD equipment for precise testing. Working with us, you will receive professional support to accelerate the commercialization of your diagnostic products.
Introduction to Autoimmune Diseases
Autoimmune diseases are a group of disorders characterized by an abnormal immune response where the body's immune system mistakenly attacks its own tissues and organs. This immune system dysfunction leads to inflammation, tissue damage, and impaired organ function. Classic examples of autoimmune diseases include rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, type 1 diabetes, etc.
Fig. 1 The actions of autoantibodies in immunopathology. (Pisetsky D S., 2023)
Biomarkers of Autoimmune Disease Diagnostics
Biomarkers play a crucial role in the diagnosis, prognosis, and monitoring of autoimmune diseases. These measurable indicators provide valuable information about disease activity, severity, and response to treatment. In the realm of autoimmune diseases, various biomarkers are utilized to aid in accurate diagnosis and management.
Autoantibodies
Autoantibodies mistakenly attack the body's own tissues, leading to autoimmune reactions, and they are commonly used as diagnostic biomarkers. For instance, antinuclear antibodies (ANA) target components of the cell nucleus and are present in diseases such as systemic lupus erythematosus, rheumatoid arthritis, and Sjögren's syndrome.
Inflammatory Markers
Inflammatory markers indicate the presence and extent of inflammation in the body, which is a common feature of many autoimmune diseases. For example, C-reactive protein (CRP) is a protein produced by the liver in response to inflammation. Elevated CRP levels are associated with autoimmune diseases and can be used to monitor disease activity.
Serum Protein Biomarkers
Serum protein biomarkers are proteins present in the blood that can indicate the occurrence of autoimmune diseases. Cytokines are signaling proteins involved in immune responses. Abnormal levels of cytokines, such as tumor necrosis factor-alpha, can indicate autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease.
Market Size of Autoimmune Disease Diagnostics
According to the latest report, the autoimmune disease diagnostics market in the United States was valued at around $2.65 billion in 2023. It is expected to reach approximately $4.48 billion by 2033, with a compound annual growth rate of 5.4% during the forecast period from 2023 to 2033.
Fig. 2 Autoimmune disease diagnostics market size. (Source: Nova One Advisor Market Research Report)
Our Services
The autoimmune disease diagnostics market is showing a year-on-year growth trend. Focusing on this field, we are dedicated to developing innovative IVD products for autoimmune diseases. Utilizing disease-specific biomarkers such as autoantibodies, inflammatory markers, and serum protein biomarkers, we specialize in creating high-precision and highly specific diagnostic reagents/kits for rare autoimmune diseases. We also develop complementary diagnostic equipment, providing a one-stop solution for autoimmune disease diagnostics development.
Types of Rare Autoimmune Diseases
| A-B |
Acquired Aplastic Anemia
Autoimmune Hemolytic Anemia
Acute Disseminated Encephalomyelitis
Autoimmune Hepatitis
Acute Hemorrhagic Leukoencephalitis
Autoimmune Hypophysitis
Adult-onset Still's Disease
Autoimmune Myocarditis
Allergic Rhinitis
Autoimmune Oophoritis
Alopecia Areata
Autoimmune Orchitis
Ankylosing Spondylitis |
Autoimmune Pancreatitis
Antiphospholipid Syndrome (APS)
Autoimmune Progesterone Dermatitis
Asthma
Autoimmune Pulmonary Alveolar Proteinosis
Autoimmune Addison's Disease
Axial Spondyloarthritis
Autoimmune Encephalitis
Balo Disease
Autoimmune Gastritis
Behcet Disease
Autoimmune Gastrointestinal Dysmotility
Bullous Pemphigoid |
| C-G |
Celiac Disease
Dermatomyositis and Polymyositis
Chronic Inflammatory Demyelinating Polyneuropathy
Discoid Lupus Erythematosus
Chronic Obstructive Pulmonary Disease
Endometriosis
Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Eosinophilic Fasciitis
Chronic Recurrent Multifocal Osteomyelitis
Evans Syndrome
Churg-Strauss Syndrome |
Febrile Infection-Related Epilepsy Syndrome
Clinically Isolated Syndrome
Glomerulonephritis
Cold Agglutinin Disease
Goodpasture's Syndrome
CREST Syndrome
Gout
Crohn's Disease
Granulomatosis with Polyangiitis
Dermatitis Herpetiformis
Graves' Disease |
| H-N |
Hashimoto's Thyroiditis
Lupus Nephritis
Henoch-Schönlein Purpura
Marfan Syndrome
Idiopathic Membranous Nephropathy
Ménière's Disease
IgA Nephropathy
Microscopic Polyangiitis
Immune Thrombocytopenia
Mixed Connective Tissue Disease
Interstitial Cystitis |
Multiple Sclerosis
Interstitial Lung Disease
Myasthenia Gravis
Juvenile Dermatomyositis
Myositis
Juvenile Idiopathic Arthritis
Necrobiosis Lipoidica
Lambert-Eaton Myasthenic Syndrome
Neuromyelitis Optica Spectrum Disorder
Linear IgA Bullous Dermatosis
Neurosarcoidosis |
| O-P |
Ocular Cicatricial Pemphigoid
Pemphigus Vulgaris
Opsoclonus-Myoclonus-Ataxia Syndrome
Pernicious Anemia
Optic Neuritis
POEMS Syndrome
Palindromic Rheumatism
Polyarteritis Nodosa
Palmoplantar Pustulosis
Polycystic Ovary Syndrome
Paraneoplastic Cerebellar Degeneration |
Polymyalgia Rheumatica
Paraneoplastic Pemphigus
Primary Biliary Cholangitis
Paroxysmal Nocturnal Hemoglobinuria
Primary Sclerosing Cholangitis
Parsonage-Turner Syndrome
Psoriasis
Pelvic Inflammatory Disease
Psoriatic Arthritis
Pemphigus Foliaceus
Pure Red Cell Aplasia |
| R-Z |
Rasmussen Encephalitis
Stiff Person Syndrome
Raynaud's Syndrome
Systemic Lupus Erythematosus
Reactive Arthritis
Systemic Lupus Erythematosus (SLE)
Recurrent Pericarditis
Systemic Sclerosis
Relapsing Polychondritis
Transverse Myelitis
Rheumatic Fever |
Type 1 Diabetes
Rheumatoid Arthritis
Ulcerative Colitis
Sarcoidosis
Undifferentiated Connective Tissue Disease
Scleroderma
Uveitis
Sjögren's Syndrome
Vasculitis
Small Fiber Neuropathy
Vitiligo |
Our IVD Product Development Services
We also provide point-of-care diagnostics and companion diagnostics development services for autoimmune diseases. These services enable rapid detection of biomarkers associated with autoimmune conditions, facilitating early diagnosis and personalized treatment strategies tailored to individual patients.
If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
References
- Pisetsky D S. Pathogenesis of autoimmune disease[J]. Nature Reviews Nephrology, 2023, 19(8): 509-524.
- Witte M, Zillikens D, Schmidt E. Diagnosis of autoimmune blistering diseases[J]. Frontiers in medicine, 2018, 5: 296.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
