Acquired immune deficiency syndrome (AIDS) continues to pose a substantial and enduring global health obstacle. Leveraging our extensive proficiency in AIDS diagnostic research, we are primed to provide customized solutions and all-encompassing support to accelerate your progression from AIDS diagnostic research to the commercialization stage.
Overview of AIDS
Acquired immune deficiency syndrome, or AIDS, represents the advanced stage of infection caused by the human immunodeficiency virus (HIV). This debilitating condition compromises the immune system, rendering individuals susceptible to a range of opportunistic infections and specific types of cancer. HIV, a retrovirus, primarily targets CD4+ T cells, gradually depleting these crucial immune cells and leading to the progression of AIDS.
Fig. 1 HIV-1 virion structure. (Rossi E, et al., 2021)
Diagnostic Biomarkers for AIDS
Diagnostic biomarkers play a crucial role in the identification, prognosis, and management of AIDS. These biomarkers are measurable indicators that aid in the early detection, monitoring, and assessment of the disease progression.
p24 Antigen
The p24 antigen is a core protein of the HIV virus. The presence of the p24 antigen indicates that the virus is actively replicating and is an important biomarker for early diagnosis, especially before HIV antibodies are produced.
HIV Antibodies
HIV antibodies are immune proteins produced by the body in response to HIV infection. HIV antibody testing is the primary method for diagnosing HIV infection and assessing immune response.
HIV RNA
HIV RNA testing involves detecting and quantifying viral RNA in the blood, thereby directly measuring viral load. This molecular test is particularly useful for monitoring viral replication dynamics and guiding therapeutic decisions.
IVD Kits for AIDS
In vitro diagnostic (IVD) kits are essential tools in the diagnosis and control of HIV. Their significance in prompt identification, disease monitoring, public health support, and research advancement highlights their vital role in combating AIDS.
| Kits |
Applications |
Detection Methods |
| HIV Antibody Detection Kits |
These kits detect antibodies produced by the immune system in response to HIV infection. They are often used for initial screening of HIV infection. |
ELISA |
| HIV Antigen Detection Kits |
These kits are typically used to detect antigens in HIV particles, such as the p24 antigen. They can be employed for early detection of HIV infection. |
Immunofluorescence or Immunochromatography |
| HIV RNA Test Kits |
HIV RNA test kits are used to detect HIV genetic material in body fluids, providing a direct measurement of viral load. |
PCR |
| CD4 Cell Count Test Kits |
These kits can quantitatively measure the number of CD4 T cells in infected individuals, which is very important for monitoring the function of the immune system. |
Flow cytometry |
Our Services
Specializing in delivering cutting-edge IVD solutions for rare infectious diseases like acquired immune deficiency syndrome (AIDS), our company is dedicated to developing tailor-made antigen, antibody, and RNA detection kits to enhance early detection and efficient control of AIDS. These kits are utilized alongside auxiliary diagnostic devices to maximize detection sensitivity and specificity.
IVD Product Development Services
Our services are not limited to this. In order to accelerate the rapid identification and individualized therapeutic options for AIDS, we offer point-of-care testing (POCT) and companion diagnostic development services. These essential services are instrumental in improving the effectiveness and precision of AIDS diagnostics, empowering the implementation of tailored care approaches for impacted individuals.
If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
Reference
- Rossi E, Meuser M E, Cunanan C J, et al. Structure, function, and interactions of the HIV-1 capsid protein[J]. Life, 2021, 11(2): 100.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
