Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease with varying severity and progression. With a team of top experts in rare diseases, we offer a wide range of rare disease diagnosis development services. These services include cutting-edge IVD products, point-of-care testing, and companion diagnostic development, all aimed at facilitating precise and prompt diagnosis of rare conditions like SLE.

Overview of Systemic Lupus Erythematosus

SLE, a systemic autoimmune disorder, manifests with a diverse array of symptoms affecting organs such as the kidneys, skin, heart, brain, and cardiovascular system. The incidence of SLE varies between 0.3 and 31.5 cases per 100,000 individuals.

In SLE, both innate and adaptive immune responses play roles. The interplay between genetic factors and environmental triggers results in various immune system changes, leading to sustained attacks on the body's genetic material. Tissue damage, triggered by autoantibodies or immune complex deposits, occurs in vital organs like the kidneys, heart, nervous system, skin, lungs, muscles, and joints, contributing significantly to morbidity and heightened mortality rates.

Fig.1 Overview of SLE. (Fanouriakis, A., et al., 2021)

Biomarkers Development for Systemic Lupus Erythematosus

Biomarkers are essential in the diagnosis of SLE, categorizing its complications, evaluating disease activity, and indicating the effectiveness of therapeutics for SLE. The advancement of SLE biomarkers has made notable strides recently. Key autoantibodies, like anti-dsDNA and anti-nuclear antibodies, are hallmark features of SLE. Each biomarker for SLE is measured at specific sites in individuals with the condition.

Fig.2 Common biomarkers for SLE. (Yu, H., et al., 2021)

IVD Kits for Systemic Lupus Erythematosus

Our Services

Our commitment to pushing the limits of rare disease diagnosis and therapy, and providing innovative solutions for conditions like SLE. By utilizing cutting-edge technologies, we can provide services for the development of IVD products that accurately detect rare diseases in their early stages, enabling swift and accurate therapy interventions.

Additionally, we also offer point-of-care testing and companion diagnostic development services to advance precise diagnosis and personalized therapy on a global scale. We are dedicated to assisting researchers and scientists by furnishing them with thorough support and resources during their diagnostic and therapeutic development processes.

If you are interested in our services, please don't hesitate to contact us.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.