The realm of herpes simplex diagnostics poses numerous challenges. Leveraging our pioneering work in herpes simplex research, we lead the way in creating state-of-the-art IVD products. Serving as your reliable partner in herpes simplex diagnostic research, we offer unmatched support tailored to fulfill your research requirements.

Overview of Herpes Simplex

Herpes simplex virus (HSV) continues to be a notable public health issue given its widespread occurrence and global impact on individuals. This virus comprises two primary types, HSV-1 and HSV-2, each possessing unique yet interconnected features. HSV-1 typically results in oral herpes, whereas HSV-2 predominantly manifests as genital herpes. Both types can manifest in various parts of the body, leading to painful lesions and recurrent outbreaks. The impact of herpes simplex infection is widespread, necessitating the urgent need for accurate diagnostic tools to manage and control the spread of the virus.

Fig. 1 Factors that enhance HSV replication in eczema herpeticum. (Damour, Alexia, et al., 2020)

Diagnostic Biomarkers for Herpes Simplex

The diagnosis of herpes simplex virus (HSV) infection is challenging due to its diverse presentations and potential for asymptomatic shedding. The development of sensitive and specific biomarkers for detecting HSV is crucial for accurate diagnosis, therapeutic monitoring, and control of transmission.

Viral proteins specific to HSV, such as glycoproteins and capsid proteins, can serve as biomarkers for the presence of virus in a specimen. Antigen detection is particularly useful for diagnosing acute HSV infections when viral shedding is high.

Antigens

Antibodies are produced by the immune system in response to HSV infection. Serological tests identify antibodies against HSV antigens, including IgM and IgG, in the bloodstream. IgM antibodies typically signify a recent or acute infection, whereas IgG antibodies indicate a prior or dormant infection.

Antibodies

DNA is a highly specific diagnostic biomarker in HSV. Detection of HSV DNA helps confirm active viral replication and monitor therapeutic response. PCR is widely used to diagnose HSV infection in a variety of sample types, including follicular fluid, swabs, and cerebrospinal fluid.

Viral DNA

IVD Kits for Herpes Simplex

In vitro diagnostic (IVD) kits are indispensable tools for diagnosing herpes simplex virus (HSV) infection. By rapidly, accurately and type-specifically detecting HSV biomarkers, IVD kits enable healthcare providers to take timely interventions, monitor disease progression, prevent complications and implement effective control measures.

Our Services

Being trailblazers in infectious disease diagnostics, we specialize in crafting advanced IVD products for herpes simplex virus (HSV) infection, customizing our services to meet intricate diagnostic demands. Our expertise includes the development of specialized IVD reagents/kits and sophisticated diagnostic devices specifically tailored for HSV infection, elevating diagnostic automation and promoting the effective management of the disease.

IVD Reagent/Kit Development

• Proof of Concept and Feasibility
• IVD Reagent/Kit Design Service

• IVD Reagent/Kit Verification Service
• IVD Reagent/Kit Optimization Service

IVD Device Development

• Preparation of Development Plan
• Prototype Design Service

• Styling Machine Development Service
• Device Verification and Optimization

We also offer point-of-care testing (POCT) and companion diagnostic development services for herpes simplex. These services enable rapid detection of biomarkers associated with herpes simplex virus (HSV), facilitating early diagnosis and personalized therapeutics for affected individuals.

If you are interested in our services, please feel free to contact us for more details and quotation information of related services.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.