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Rotavirus Infection

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Rotavirus Infection

Rotavirus infection is a major public health problem worldwide. Through our groundbreaking work in rotavirus research, we lead the way in creating innovative IVD solutions to improve the management of this infection. Serving as your reliable ally in rotavirus infection diagnostic research, we offer unmatched assistance to address your research requirements effectively.

Introduction to Rotavirus Infection

Rotavirus infection is a highly contagious gastrointestinal infection that primarily affects children. The virus is known for causing gastroenteritis, with symptoms including severe diarrhea, vomiting, fever and loss of appetite, leading to dehydration in young people. Rotavirus is transmitted through hand-to-mouth contact with infected fecal matter. The development of accurate and convenient diagnostic tools is essential for the early identification of rotavirus and effective control of the disease.

Schematic diagram of the pathogenesis of rotavirus infection.Fig. 1 Pathogenesis of rotavirus infection. (Gonzalez-Ochoa, Guadalupe, et al., 2017)

Diagnostic Biomarkers for Rotavirus Infection

Diagnostic biomarkers for rotavirus infection act as quantifiable signals indicating the virus's presence within the body. Identifying distinct biomarkers linked to rotavirus infection aids in validating the diagnosis, distinguishing rotavirus from alternative causes of gastroenteritis, and tracking the evolution of the disease.

Rotavirus Antigens

Rotavirus antigens, such as viral proteins VP6 and VP7, are commonly used as biomarkers for diagnostic tests. These antigens can be detected in stool samples using immunoassays, providing a rapid and specific means of identifying rotavirus infections.

Viral RNA

The presence of rotavirus RNA in biological specimens, detected through molecular diagnostic techniques like PCR, is a sensitive biomarker for rotavirus infection. Viral RNA serves as a direct indicator of active viral replication and can aid in the early diagnosis of rotavirus.

IVD Kits for Rotavirus Infection

In vitro diagnostic (IVD) kits are indispensable tools for diagnosing rotavirus infection. These kits are typically formulated based on specific biomarkers and employ convenient detection methods. They can effectively provide accurate test results, which not only helps timely therapeutic intervention but also contributes to effective epidemic control.

Rotavirus Antigen Rapid Test Kit

The kit uses a lateral flow chromatography immunoassay for the qualitative detection of rotavirus antigens in stool samples.

Rotavirus RNA Detection Kit

The kit is an IVD test based on real-time PCR technology for the qualitative detection and differentiation of norovirus genogroups and rotavirus-specific RNA in stool samples.

Our Services

By conducting extensive research on the pathogenesis and diagnostic biomarkers associated with rotavirus infection, we are dedicated to creating groundbreaking IVD solutions aimed at precisely detecting and efficiently controlling this infectious diseases. Our services include the development of RNA and antigen detection kits as well as complementary diagnostic devices. Our goal is to revolutionize rotavirus diagnostics by creating cutting-edge IVD products.

In order to expedite swift diagnosis and tailored therapeutics for rotavirus infection, we offer point-of-care testing (POCT) and companion diagnostic development services. These services are vital for enhancing the precision and efficiency of diagnosing rotavirus infection, and for devising individualized care strategies for those affected.

If you are interested in our services, please don't hesitate to reach out to us for further information and pricing details on the services we offer.

Reference

  1. Gonzalez-Ochoa, Guadalupe, et al. "Modulation of rotavirus severe gastroenteritis by the combination of probiotics and prebiotics." Archives of microbiology 199 (2017): 953-961.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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