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Infectious Diseases

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Infectious Diseases

Rare infectious diseases face unique challenges in terms of diagnosis. Our company has always been at the forefront of diagnostic solutions for such illnesses. By leveraging advanced technologies in point-of-care diagnostics, we develop customized antigen and microbial detection reagents/kits for rare infectious diseases, facilitating early identification of pathogens and rapid control of infections.

Overview of Infectious Diseases

Rare infectious diseases encompass a diverse group of illnesses caused by pathogens such as bacteria, viruses, parasites, and fungi. These conditions are characterized by their low incidence rate, making them particularly challenging to diagnose effectively. Below are some of the challenges facing rare infectious disease diagnostics.

Laboratory Testing Limitations

Specialized laboratories capable of diagnosing rare infectious diseases may not be readily available in all geographic regions, leading to delays in obtaining accurate test results.

Differential Diagnosis Challenges

Rare infectious diseases may share symptoms with more prevalent conditions, making it challenging to differentiate between the two without targeted diagnostic testing.

Emerging Pathogens

The rapid mutation of pathogens, coupled with the issue of antibiotic resistance, leads to the swift evolution of sources of infection, posing challenges to accurate diagnosis.

Market Analysis of Infectious Disease Diagnostics

In 2022, the infectious disease diagnostic market size was $24 billion. It is projected that the compound annual growth rate from 2023 to 2032 will exceed 5.5%. The increasing popularity of point-of-care diagnostic testing will drive industry growth.

Point-of-care testing of patient samples.Fig. 1 Flow diagram showing the process of sample testing using point-of care devices. (Nath P, et al., 2020)

Point-of-care Diagnostic Development for Infectious Diseases

Point-of-care (POC) diagnostics are medical tests performed at or near the point of patient care. These tests are designed to provide rapid results, enabling immediate clinical decisions for patients. POC diagnostics contribute to early detection of rare infectious diseases, playing a crucial role in timely interventions for diseases and epidemic control.

Rapid Antigen Tests

These tests detect the presence of specific proteins (antigens) on the surface of pathogens, such as viruses or bacteria, providing quick results for infections like influenza or COVID-19.

Lab-on-a-Chip Devices

Microfluidic devices that integrate multiple laboratory functions on a single chip, enabling rapid and automated sample processing for various diagnostic applications.

Lateral Flow Assays

These tests detect the presence of a target analyte in a sample using capillary action, commonly used for rapid detection of biomarkers, antibodies, or pathogens.

Our Services

Our company is dedicated to driving innovation in rare infectious disease diagnostic development, addressing unmet diagnostic needs, and advancing precision medicine. We specialize in designing antigen and microbial detection reagents/kits tailored for rare infectious diseases. By integrating technologies related to point-of-care diagnostics, we are able to offer portable and user-friendly diagnostic products for the rapid diagnosis of rare infectious diseases, thereby enhancing diagnostic efficiency and accuracy.

Types of Rare Infectious Diseases

A-D
Acinetobacter Infection Chikungunya
Acquired Immune Deficiency Syndrome (AIDS) Chlamydia
Actinomycosis Chlamydia Infection
Adenovirus Infection Clostridioides Difficile Infection
African Trypanosomiasis Coronavirus Disease 2019 (COVID-19)
Amoebiasis Creutzfeldt-Jakob Disease (CJD)
Angiostrongyliasis Crimean-Congo Hemorrhagic Fever (CCHF)
Anthrax Cryptococcosis
Brucellosis Cryptosporidiosis
Burkholderia Infection Cytomegalovirus Infection
Buruli Ulcer Dengue Fever
Chagas Disease Dientamoebiasis
Chickenpox Diphtheria
E-H
Ebola Virus Disease (EVD) Hantavirus Pulmonary Syndrome
Echinococcosis Heartland Virus Disease
Ehrlichiosis Helicobacter Pylori
Enterococcus Infection Hemolytic-uremic Syndrome (HUS)
Enterovirus Infection Hemorrhagic Fever with Renal Syndrome (HFRS)
Epidemic Typhus Hendra Virus Infection
Epstein–Barr Virus Infectious Mononucleosis Hepatitis
Fasciolasis Herpes Simplex
Glanders Histoplasmosis
Gonorrhea Hookworm Infection
Group A Streptococcal Infection (GAS Infection) Human Papillomavirus Infection
Haemophilus Influenzae Infection Human T-Lymphotropic Virus Type 1 (HTLV-1)
Hand, Foot and Mouth Disease (HFMD) Hymenolepiasis
I-N
Invasive Aspergillosis Marburg Hemorrhagic Fever (MHF)
Isosporiasis Marburg Virus Disease
Japanese Encephalitis Measles
Kingella Kingae Infection Melioidosis
Kuru Meningitis
Lassa Fever Meningococcal Disease
Legionellosis Metagonimiasis
Leishmaniasis Microsporidiosis
Leprosy Middle East Respiratory Syndrome (MERS)
Leptospirosis Mycoplasma Pneumoniae Infection
Lyme Disease Neonatal Conjunctivitis
Lymphatic Filariasis Nipah Virus Infection
Lymphocytic Choriomeningitis Nocardiosis
Malaria Norovirus
O-Z
Pertussis (Whooping Cough) Sporotrichosis
Plague Streptococcal Infections
Pneumococcal Infection Syphilis
Poliomyelitis Taeniasis
Psittacosis Tetanus
Q Fever Toxoplasmosis
Rabies Trachoma
Respiratory Syncytial Virus Infection Trichomoniasis
Rift Valley Fever Tuberculosis
Rotavirus Infection Typhoid Fever
Rubella West Nile Virus
Salmonellosis Yellow Fever
Schistosomiasis Yersinia Pseudotuberculosis Infection
Severe Acute Respiratory Syndrome (SARS) Zika Fever

Workflow of IVD Reagent/Kit Development

Workflow of IVD Device Development

To achieve precision treatment for rare infectious diseases, we provide companion diagnostic development services. These services can help identify the most effective treatment options for patients by analyzing specific biomarkers or genetic markers associated with the disease.

If you are interested in our services, please feel free to contact us for more details and quotation information of related services.

References

  1. Nath P, Kabir A, Khoubafarin Doust S, et al. Detection of bacterial and viral pathogens using photonic point-of-care devices[J]. Diagnostics, 2020, 10(10): 841.
  2. Wang C, Liu M, Wang Z, et al. Point-of-care diagnostics for infectious diseases: From methods to devices[J]. Nano Today, 2021, 37: 101092.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.